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以４０例正常人为对照，用放射性核素显像研究５０例急性或陈旧性心肌梗塞（ＭＩ）病人的左室ＭＩ部位、心肌梗塞面积（ＭＩＳ）及其对左、右心室功能的影响．方法：以左、右室射血分数（ＬＶＥＦ、ＲＶＥＦ）、最大射血率（ＰＥＲ）及最大充盈率（ＰＦＲ）作为心功能指标，用角度法测算ＭＩＳ．根据左室ＭＩ部位不同分为Ⅰ组（前壁及心尖部）、Ⅱ组（侧壁）和Ⅲ组（下壁及后壁）．并进行统计学分析．结果：Ⅰ组及Ⅱ组中ＬＶＥＦ重度下降者分别为８１．５％和６０．０％，Ⅰ组及Ⅲ组中ＲＶＥＦ重度下降者分别为２０．０％和５７．２％．Ⅰ组及Ⅱ组中ＭＩＳ与ＬＶＥＦ呈负相关（ｒ＝-０．６８），Ⅲ组中ＭＩＳ与ＲＶＥＦ呈负相关（ｒ＝-０．５１）．其中２０例大面积ＭＩ（ＭＩＳ５３．８３％±９．７４％）病人ＭＩＳ与ＬＶＥＦ呈负相关（ｒ＝-０．７２），而与ＲＶＥＦ呈正相关（ｒ＝０．６４）．结论：了解ＭＩ部位及ＭＩＳ可对心功能作出较为客观的估价．同时，了解心功能状态可初步估算ＭＩＳ的大小，有利于诊断和治疗疾病及判断病情的预后．关键词
Forty normal subjects were used as control and the radionuclide imaging was used to study the changes of left ventricular MI, myocardial infarct size (MIS) and left and right ventricular function in 50 patients with acute or old myocardial infarction (MI). Methods: Left and right ventricular ejection fraction (LVEF, RVEF), maximum ejection rate (PER) and maximum perfused rate (PFR) were used as the indexes of cardiac function. According to the left ventricular MI site is divided into Ⅰ group (anterior and apical), Ⅱ group (side wall) and Ⅲ group (lower wall and posterior wall). And statistical analysis. Results: The severe decrease of LVEF in group Ⅰ and group Ⅱ was 81.5% and 60.0% respectively. The severe decrease of RVEF in group Ⅰ and group Ⅲ was 20.0% and 57.2% respectively. There was a negative correlation between MIS and LVEF in group Ⅰ and group Ⅱ (r = -0.68). There was a negative correlation between MIS and RVEF in group Ⅲ (r = -0.51). MIS was negatively correlated with LVEF (r = -0.72), but positively correlated with RVEF (r = 0.64) in 20 patients with large area MI (MIS53.83% ± 9.74%). Conclusion: Understanding MI and MIS can make a more objective assessment of cardiac function. At the same time, to understand the status of cardiac function can be a preliminary estimate of the size of MIS is conducive to the diagnosis and treatment of disease and prognosis of the disease. Key words