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随着水产养殖业的不断发展，抗生素在水产养殖上的应用越来越广泛，抗生素的应用有效地控制了许多水产疾病的发生，极大地促进了水产养殖业的发展。但是，由于抗生素的使用容易产生耐药菌株，存在药物残留以及容易破坏水生动物微生态平衡，使得水产养殖病害防治工作越加困难，?
With the constant development of aquaculture, the application of antibiotics in aquaculture is more and more widely. The application of antibiotics has effectively controlled many aquatic diseases and greatly promoted the development of aquaculture. However, due to the use of antibiotics prone to drug-resistant strains, the existence of drug residues and easy to destroy the micro-ecological balance of aquatic animals, making aquaculture disease prevention and control more difficult ,?