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目的探讨复方地芬诺酯在腹腔镜辅助全盆重建术中对肠蠕动的抑制效果。方法选择2010年1月-2013年5月我院腹腔镜辅助全盆底重建术且随访资料完整的患者60例。根据随机数字表法分为A和B两组(n=30),A组术前30min口服复方地芬诺酯10mg,B组口服相同形状安慰剂。结果 A组患者肠道蠕动抑制明显、手术时间短、周围组织损伤少,与B组相比差异具有统计学意义(P<0.05),A组患者术后排气时间未见延长、腹胀便秘的患者例数未增加,两组相比差异无统计学意义(P>0.05)。结论腹腔镜辅助全盆重建术中使用复方地芬诺酯抑制肠道运动,扩大手术操作空间,创造良好的操作环境具有安全可靠,并发症少等优点。
Objective To investigate the inhibitory effect of compound diphenoxylate on intestinal peristalsis in laparoscopic assisted pelvic reconstruction. Methods From January 2010 to May 2013 in our hospital laparoscopic assisted pelvic floor reconstruction and follow-up data of 60 patients complete. According to the random number table divided into A and B two groups (n = 30), A group 30min oral diphenoxylate oral compound 10mg, B group oral administration of the same shape placebo. Results A group of patients with intestinal peristalsis was significantly inhibited, the operation time is short, the surrounding tissue less damage, compared with the B group, the difference was statistically significant (P <0.05), A group of patients with no postoperative exhaust time extended abdominal constipation The number of patients did not increase, no significant difference between the two groups (P> 0.05). Conclusion laparoscopic assisted pelvic reconstruction using diphenoxylate to inhibit intestinal motility, to expand the space for surgical operations, to create a good operating environment with safe, reliable, less complications and so on.