体外药理学实验是中药防治代谢性骨病研究的重要方面之一 ,而药物添加方法一直是研究者们关注的焦点 ,近年来 ,含药血清方法开始受到重视 ,本文就这一方法的研究进展及其在中药调节骨与软骨代谢基础研究中的应用概况进行了回顾与思考。1　含药血清方法概况　　长期以来 ,中药体 In vitro pharmacology experiments are one of the most important aspects of TCM prevention and treatment of metabolic bone diseases, and drug addition methods have always been the focus of researchers. In recent years, the serum-containing method has begun to receive attention. This article focuses on the progress of this method. And its application in traditional Chinese medicine to regulate the basic research of bone and cartilage metabolism was reviewed and considered. 1 Drug-containing serum method for a long time, Chinese medicine body