慢性丙型肝炎合并干眼患者抗病毒治疗的临床分析

来源 :皖南医学院学报 | 被引量 : 0次 | 上传用户:lfzmj
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目的:探讨慢性丙型肝炎(CHC)合并干眼患者抗病毒治疗的临床效果。方法:对慢性丙型肝炎合并干眼患者34例(无干眼患者37例作为对照)均应用聚乙二醇干扰素α-2a联合利巴韦林治疗,观察两组病毒学应答率及不良反应。结果:1干眼组完全早期病毒学应答(c EVR)、治疗结束时病毒学应答(ETVR)、持续病毒学应答(SVR)均低于对照组,差异有统计学意义(P〈0.05);2干眼组治疗结束后干眼患病率37.9%,较治疗前差异有统计学意义(P〈0.05);3干眼组中性粒细胞〈0.75×109/L和干扰素〉80
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