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甲状旁腺素(PTH)的靶器宫有骨、消化道和肾脏。PTH在肾脏的作用机制是通过活化腺苷酸环化酶增加细胞内“第二信使”环腺苷酸的浓度,抑制肾小管磷酸盐的回吸收,从而间接增加钙的回吸收,使血钙浓度升高。因此,在肾小球滤过量正常的情况下,尿环腺苷酸(UCAMP)浓度可作为PTH终端效应的精确指标。外科医生可通过术中彻底探查和对腺体大小及与功能的关系的正确估价,在切除高功能的腺体的同时保留正常的腺体,从而使85%～95%的原发性甲状旁
Parathyroid hormone (PTH) target palace have bone, digestive tract and kidney. The mechanism of PTH in the kidney is to increase the concentration of cyclic adenosine monophosphate in the cell by activating adenylate cyclase and inhibit the renal tubular phosphate back to absorb, Increased concentration. Therefore, urinary cyclic adenosine monophosphate (UCAMP) concentration can be used as an accurate indicator of the terminal effect of PTH with normal glomerular filtration. Surgeons with 85% to 95% of primary parathyroid by extensive probing during surgery and correct assessment of glandular size and functional relationship retain the normal gland while removing high-functioning glands