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为了探讨在白念珠菌所致系统性感染中是否存在保护性抗体免疫，本研究采用细胞融合、细胞培养、动物实验等技术，制备抗白念珠菌胞壁外膜成份单克隆抗体，在感染动物模型上筛选出具有保护作用的单抗，探讨其保护作用机制等。主要取得以下结果：1．建立了3株分泌抗白念珠菌胞壁
In order to investigate whether there is protective antibody immunity in systemic infection caused by Candida albicans, monoclonal antibodies against Candida albicans cell envelope were prepared by cell fusion, cell culture and animal experiments, The model was screened to have a protective effect of monoclonal antibody to explore its protective mechanism. The main results are as follows: 1. Three strains of Candida albicans secreting cell wall were established