莫西沙星致血小板减少性紫癜

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1例31岁男性患者因肺部感染给予莫西沙星400 mg口服、1次/d。用药9 d后出现咯血、便血和全身散在瘀点、瘀斑,血小板计数(PLT)1×10n 9/L,诊断为血小板减少性紫癜。停用莫西沙星,给予止血、重组人白细胞介素11及输注浓缩血小板等治疗。治疗6 d后,患者全身淤点、瘀斑消退,PLT 376×10n 9/L。骨髓穿刺结果提示为免疫性血小板减少症。n “,”A 31-year-old male patient received moxifloxacin 400 mg orally once daily for pulmonary infection. After 9 days of treatment, the patient developed hemoptysis, hematochezia, and scattered petechia and ecchymosis on his body, with platelet count (PLT) 1×10n 9/L. Thrombocytopenic purpura was diagnosed. Moxifloxacin were stopped and treatments such as hemostasis, recombinant human interleukin-11, and an IV infusion of concentrated platelets were given. Six days later, the patient′s petechia and ecchymosis disappeared and the PLT was 376×10n 9/L. Bone marrow puncture result showed that it was immune thrombocytopenia.n
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