很多文章只强调了血管紧张素转换酶抑制剂治疗高血压和严重心衰的有益的血流动力学作用,而对钾的内环境稳定的影响则报道甚少。作者报道2例充血性心衰患者,因服用巯甲丙脯酸和羧苯丙脯酸(enala-pril)以及停药激发并加剧了血钾浓度变化而导致心跳骤停。例1为62岁男性,冠心病伴严重心衰。用羧苯丙脯酸治疗,临床症状明显改善。用药三个月后心导管检 Many articles highlight the beneficial hemodynamic effects of angiotensin-converting enzyme inhibitors in the treatment of hypertension and severe heart failure, but little is known about the effects of potassium on the homeostasis. The authors report that cardiac arrest occurred in 2 patients with congestive heart failure as a result of taking captopril and enalapril and stopping withdrawal and aggravating changes in serum potassium levels. Case 1 was a 62-year-old man with coronary heart disease with severe heart failure. Treatment with carboxypropionate significantly improved clinical symptoms. Cardiac catheterization after three months of medication