血卟啉衍生物(HPD)作为光敏剂,在诊治恶性肿瘤的化学、药理基础及临床研究方面进行了广泛的研究,并在浅表肿瘤的光敏治疗上取得了可喜疗效。但光敏治疗除皮肤外,对其它组织的光射深度及其剂量分布的测定尚缺少可靠数据,激光的弱穿透性限制了光敏治疗的适应证范围。Cohen As a photosensitizer, hematoporphyrin derivative (HPD) has been extensively studied in the chemistry, pharmacology, and clinical research of the diagnosis and treatment of malignant tumors, and has achieved encouraging results in the phototherapy of superficial tumors. However, in addition to the skin, there are still no reliable data for the measurement of the depth of light and dose distribution of other tissues. The weak penetration of the laser limits the scope of indications for phototherapy. Cohen