目的探讨介入热灌注化疗栓塞术治疗肝脏恶性肿瘤的疗效。方法对31例肝脏肿瘤患者先经导管缓慢推注小剂量5-Fu,再用中等剂量丝裂霉素与顺铂或卡铂联合经动脉灌注行热化疗(使进入体内温度达到43～48℃),并用阿霉素或表阿霉素与超液态碘油按5∶1的比例混合,栓塞肿瘤供血血管。结果介入热化疗栓塞术后,患者临床症状迅速缓解,碘油均匀弥散并延长充填时间。31例中完全缓解3例,部分缓解11例,轻度缓解8例,无效9例,总缓解率为71%。结论介入热化疗栓塞术是治疗肝脏恶性肿瘤的一种重要方法之一。 Objective To evaluate the efficacy of interventional hyperthermic perfusion chemoembolization for the treatment of hepatic malignancies. Methods Thirty-one patients with hepatic tumors were given a low dose of 5-Fu via catheter, followed by a moderate dose of mitomycin and cisplatin or carboplatin combined with intra-arterial infusion of thermochemotherapy (into the body temperature of 43-48 °C). ), and mixed with adriamycin or epirubicin and ultra-liquid lipiodol in a ratio of 5:1 to embolize tumor blood vessels. Results After interventional thermochemoembolization, the clinical symptoms of the patients quickly relieved, and the lipiodol dispersed evenly and prolonged the filling time. In 31 cases, 3 cases were completely relieved, 11 cases were partially relieved, 8 cases were slightly relieved, 9 cases were ineffective, and the total remission rate was 71%. Conclusion Interventional thermochemotherapy embolization is one of the most important methods to treat hepatic malignancy.