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经检查,某所人群周围血象异常改变的特点是:白细胞总数增高、中性粒细胞百分比降低、淋巴和单核细胞增多。除部分血象异常者伴脾、肝肿大外,无一例发烧及临床表现。检测93份血清中EB病毒(Epstein-BarrVirus简称EBV)IgM抗体,全部阴性;35例嗜异性凝集试验及豚鼠肾吸收试验均为阴性,从而排除EBV感染。微量补体结合法测定52份巨细胞病毒(Cytomegalovirus简称CMV)血清抗体滴度呈4倍以上增高者18份,阳转率34.6%。说明近期有CMV感染或潜伏性感染复燃,确定1066例异常血象为一次CMV隐性感染引起的类传染性单核细胞增多症流行。
After examination, a group of peripheral blood abnormal changes are characterized by: the total number of leukocytes increased, the percentage of neutrophils decreased, lymphocytes and monocytes increased. In addition to some abnormal blood with spleen, hepatomegaly, no fever and clinical manifestations. Ninety-three serum samples of Epstein-Barr virus (EBV) IgM were negative, all of them were negative. 35 cases of heterophilic agglutination test and guinea pig kidney absorption test were negative, thus excluding EBV infection. Trace complement fixation method for the determination of 52 cytomegalovirus (Cytomegalovirus referred CMV) serum antibody titers were more than 4 times higher than 18, the positive conversion rate of 34.6%. Description of CMV infection or latent infection in the recent resurgence, identified 1066 cases of abnormal blood as a CMV latent infection caused by infectious mononucleosis epidemic.