论文部分内容阅读
目的探讨坎地沙坦对高血压患者血压晨峰现象的影响。方法对服用国产氨氯地平后仍有血压晨峰现象的60例高血压患者晚间加服坎地沙坦,观测服药前及服药后1、3个月的清晨血压变化。结果晚间加服坎地沙坦后,晨间血压均有明显下降(P<0.05),服药后3个月的血压下降值高于1个月时的血压下降值,但差异无统计学意义(P<0.05),降压达标率为85%。结论在服用国产氨氯地平的同时,晚间加服坎地沙坦,能够有效控制高血压患者的晨峰现象。
Objective To investigate the effect of candesartan on the morning peak of blood pressure in hypertensive patients. Methods Sixty patients with hypertension who still had the morning peak of blood pressure after taking amlodipine were given candesartan evening, and the changes of blood pressure before and after taking medicine were observed. Results After oral administration of candesartan, morning blood pressure was significantly decreased (P <0.05), 3 months after taking the blood pressure was higher than 1 month when the blood pressure decreased, but the difference was not statistically significant P <0.05), the standard rate of 85%. Conclusions While taking domestic amlodipine, taking candesartan at night can effectively control the morning peak of hypertensive patients.