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对20例扩张型心肌病患者心内膜心肌活检组织进行形态学观察,认为其在光镜和电镜下的形态改变也见于风心和先心患者;其中10例作组化半定量检查与18例心功能正常的先心者比较,两组间组化累积分数有显著差异,心肌病组肌球蛋白ATP酶活力明显降低,认为该酶活力的下降是继发于心功能的变化。
Endomyocardial biopsy in 20 patients with dilated cardiomyopathy was observed morphologically, and the morphological changes of endocardial myocardium were also observed in patients with rheumatic heart and congenital heart disease. Among them, 10 patients underwent semi-quantitative histochemistry examination and 18 In patients with normal heart function, there was a significant difference in the cumulative scores between the two groups. The activity of myosin ATPase in cardiomyopathy group was significantly lower. It is considered that the decrease of activity of this enzyme is secondary to the change of cardiac function.