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目的:探讨法舒地尔注射液对冠心病患者心电图QT离散度(QTd)的影响。方法:将深圳市人民医院2008年1月至2013年12月收治的冠心病患者200例随机分为对照组(n=100)和治疗组(n=100),治疗组在对照组常规治疗的基础上加用法舒地尔注射液60 mg/d,比较治疗2周后两组QTd变化及心律失常发生率。结果:与治疗前比较,两组治疗后QTd及心律失常发生率均明显降低(P<0.05),且治疗组较对照组更显著(P<0.01)。结论 :在冠心病常规治疗的基础上佐以法舒地尔注射液能显著减少其QTd和心律失常发生率。
Objective: To investigate the effect of fasudil injection on QTd in patients with coronary heart disease. Methods: 200 patients with coronary heart disease admitted to Shenzhen People’s Hospital from January 2008 to December 2013 were randomly divided into control group (n = 100) and treatment group (n = 100). The treatment group in the control group received routine treatment Based on the addition of fasudil injection 60 mg / d, compared two weeks after treatment QTd changes and arrhythmia incidence. Results: Compared with those before treatment, the incidences of QTd and arrhythmia were significantly decreased in both groups (P <0.05), and the treatment group was more significant than the control group (P <0.01). Conclusion: Fasudil injection can significantly reduce the incidence of QTd and arrhythmia on the basis of routine treatment of coronary heart disease.