慢性肾功能衰竭(CRF)的各个阶段都常有不同程度的高血压,终末期肾(ESRD)高血压发病率占80％～90％。由于高血压的产生与心输出量和总外周血管阻力有关,即平均动脉压=心输出量×总外周血管阻力(BP=CO×TPR)。因此,CRF时,无论CO或TPR增加,都能使血压升高。 CRF时影响血压的因素 (一)影响心输出量改变包括:①细胞外液容量的改变,受钠平衡、血管紧张素Ⅱ、 Various stages of chronic renal failure (CRF) often have different levels of hypertension, the incidence of end-stage renal disease (ESRD) hypertension accounts for 80% to 90%. Hypertension is associated with cardiac output and total peripheral vascular resistance, ie, mean arterial pressure = cardiac output × total peripheral vascular resistance (BP = CO × TPR). Therefore, CRF, regardless of CO or TPR increased, can make blood pressure. CRF factors affecting blood pressure (A) changes affecting cardiac output include: ① changes in extracellular fluid volume, sodium balance, angiotensin Ⅱ,