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目的:探讨微信APP上门护理服务对胃癌患者自我管理能力的影响。方法:选取该院2018年1月至2019年1月收治的胃癌患者120例，随机分为对照组和观察组各60例。对照组患者接受常规护理，观察组患者在常规护理基础上接受微信APP上门护理。比较两组患者自我管理能力、自我效能、负性情绪及生活质量。结果:两组患者护理后自我管理能力得分均较护理前升高，且观察组患者健康知识水平、自我概念、自我责任感、自我护理技巧得分均显著高于对照组(n P<0.05)。两组患者护理后自我效能得分均较护理前升高，且观察组患者日常生活、健康行为、服药、遵医行为得分均显著高于对照组(n P<0.05)。两组患者护理后HAMA及HAMD得分均较护理前降低，且观察组患者HAMA及HAMD得分均显著低于对照组(n P<0.05)。两组患者护理后生活质量得分均较护理前升高，且观察组患者的躯体功能、情绪功能、社会功能、认知功能、角色功能得分均显著高于对照组(n P<0.05)。n 结论:微信APP上门护理服务是提高胃癌患者自我管理能力、自我效能、生活质量有效途径，可作为日常院外护理措施。“,”Objective:To explore the influence of WeChat APP door-to-door nursing service on the self-management ability of gastric cancer patients.Methods:A total of 120 patients with gastric cancer admitted to this hospital from January 2018 to January 2019 were randomly divided into control group and observation group, 60 cases in each group.The control group received routine nursing, while the observation group received Wechat APP door-to-door nursing.Then the self-management ability, self-efficacy, negative emotion and quality of life were compared between the two groups.Results:After nursing, the scores of self-management ability of patients in both groups were higher than those before nursing, and the scores of health knowledge level, self-concept, self-responsibility and self-nursing skills in the observation group were significantly higher than those in the control group(n P<0.05). After nursing, the self-efficacy scores of patients in both groups were higher than those before nursing, and the scores of daily life, health behavior, medication and compliance behavior of patients in the observation group were significantly higher than those in the control group (n P<0.05). After nursing, HAMA and HAMD scores of patients in both groups were lower than those before nursing, and HAMA and HAMD scores of patients in the observation group were significantly lower than those in the control group (n P<0.05). The scores of quality of life of patients in the two groups were higher than those before nursing, and the scores of physical function, emotional function, social function, cognitive function and role function in the observation group were significantly higher than those in the control group (n P<0.05).n Conclusions:WeChat APP door-to-door nursing service is an effective way to improve the self-management ability, self-efficacy and life quality of patients with gastric cancer, and can be used as a daily out-of-hospital nursing measure.