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本文报道了在位移试剂Ｅｕ（ＦＯＤ）３、Ｅｕ（ＴＦＣ）３和Ｅｕ（ＨＦＣ）３存在下非洛地平质子信号的镧诱导位移（ＬＩＳ）值，非洛地平的芳氢质子信号得到简化并解析；在手性位移试剂Ｅｕ（ＨＦＣ）３存在下，观察到甲酯的甲基明显的对映体位移差值（△△δ），据此，可对非洛地平直接进行对映体的含量分析。当Ｅｕ（ＨＦＣ）３：非洛地平为０．６２０（摩尔比）时，甲酯甲基的Ｒ和Ｓ对映体两峰的峰谷高度为峰高的３．８％，即当对映体之一的含量不低于３．８％时，可对非洛地平的对映体含量进行精确的直接测定。
This paper reports the lanthanum induced displacement (LIS) values of felodipine proton signals in the presence of the displacement reagents Eu (FOD) 3, Eu (TFC) 3 and Eu (HFC) 3. (ΔΔδ) of the methyl group of methyl ester in the presence of the chiral shift reagent Eu (HFC) 3, whereby the direct enantiomeric reaction of felodipine Content analysis. When Eu (HFC) 3: felodipine is 0.620 (molar ratio), the peak heights of the R and S enantiomers of the methyl ester methyl ester are 3.8% of the peak height, When the content of one is not less than 3.8%, the enantiomeric content of felodipine can be accurately and directly determined.