柠檬菌属(Citrobacter)是革兰氏阴性需氧菌,正常存在于土壤、水以及人和动物的肠道内。近年来,柠檬菌属的致病意义已被认识,此菌属包括弗劳地柠檬菌(C.freundii)、异样柠檬菌(C.diversus),会引起腹内、泌尿道和肺部感染。作者以前的观察认为柠檬菌属很少来源于结肠,为了验证这一设想,本文回顾美国麻省总医院1974年9月～1975年2月和1980年10月～1981年3月的柠檬菌属腹内感染和菌血症的临床资料。此外,还对13种抗生素进行敏感试验,以确定最合适的抗生素疗法。诊断标准,凡血培养阳性者属于菌血症,有噁心、呕吐、厌食、体重减轻、腹痛、发热、反跳痛以及下列情况之一者,则为腹内感染:①胆汁或腹液培养检出柠檬菌;② Citrobacter is a Gram-negative aerobic bacterium that normally resides in the gut of soil, water and humans and animals. In recent years, the pathogenic significance of the lemon genus has been known, and the genus includes C. freundii and C. diversus, causing intra-abdominal, urinary and pulmonary infections. The authors previous observations that lemon genus rarely originated in the colon, in order to verify this idea, this article reviews the Massachusetts General Hospital in September 1974 ~ February 1975 and October 1980 ~ March 1981 lemon bacteria Intra-abdominal infection and bacteremia clinical data. In addition, 13 antibiotics were also tested for sensitivity to determine the most appropriate antibiotic therapy. Diagnostic criteria, where blood culture positive persons who belong to the bacteremia, nausea, vomiting, anorexia, weight loss, abdominal pain, fever, rebound tenderness and one of the following circumstances, the intra-abdominal infection: ① bile or abdominal culture test Lemongrass; ②