体外培养人肺癌细胞经３０μｇ／ｍｌ榄香烯乳作用后，生长受到抑制，３Ｈ－ＴｄＲ、３Ｈ－ｕＲ掺入率明显下降；流式细胞分析发现该药作用７２小时后Ｇ０／Ｇ１期细胞比例上升，Ｓ期比例下降；光镜、电镜观察可见药物作用后癌细胞增殖减慢，缩小变圆。微绒毛减少。核浆比例下降，异染色质增多。由此提示，榄香烯乳可在细胞生物学及形态学水平逆转人肺癌细胞的表型，诱导这些细胞趋于分化。 After in vitro cultured human lung cancer cells were treated with 30μg/ml elemene, the growth was inhibited, the 3H-TdR and 3H-uR incorporation rate decreased significantly, and flow cytometry analysis showed that the ratio of G0/G1 phase cells after 72 hours of action of the drug. Ascended, the proportion of S phase decreased; observed by light and electron microscopy, the proliferation of cancer cells slowed down and rounding was reduced. Microvilli decreased. The proportion of nuclear plasma decreased and heterochromatin increased. This suggests that Elemene milk can reverse the phenotype of human lung cancer cells at the level of cell biology and morphology, and induce these cells to tend to differentiate.