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目的探讨Kallmann综合征诊疗方法。方法回顾分析我院4例Kallmann综合征临床资料结合文献加以分析,其中嗅觉丧失1例,伴有一侧耳听力障碍1例,智力低下1例,同时给予促性腺激素和性激素替代联合治疗。结果4例患者第二性征有不同程度的发育和改善,年龄最小1例患者治疗后精液检查存在精子。结论早期及时正确诊断和给予激素替代治疗,可以最大限度地缓解患者的临床症状并使其获得生育能力。
Objective To investigate the diagnosis and treatment of Kallmann’s syndrome. Methods Retrospective analysis of 4 cases of Kallmann’s syndrome in our hospital clinical data combined with the literature to be analyzed, including loss of smell in 1 case, accompanied by one side of the ear hearing impairment in 1 case, mental retardation in 1 case, given gonadotropin and sex hormone replacement combined treatment. Results 4 patients with secondary sexual characteristics have different degrees of development and improvement, the youngest one case after treatment of sperm in the presence of sperm. Conclusions Early timely and correct diagnosis and administration of hormone replacement therapy can alleviate the patient’s clinical symptoms and make them fertile.