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目的探讨癫痫持续状态(SE)的病因、临床救治的方法及疗效。方法分析13例癫痫持续状态发病的原因,采用静脉注射,肌注加口服或鼻饲抗癫痫药物,尽快控制癫痫发作的疗法。结果5例于发作1小时内控制,5例于1～2小时控制,3例于6～24小时控制。均未留下神经功能缺损。结论地西泮联合苯巴比妥钠是控制癫痫持续状态的首选用药;丙戊酸钠对需观察意识的癫痫持续状态患者,疗效肯定;对常规治疗无效者,咪达唑仑及异丙酚均可以有效控制发作。
Objective To investigate the etiology, clinical treatment and efficacy of status epilepticus (SE). Methods Thirteen cases of epileptic seizures were analyzed retrospectively. Intravenous injection, intramuscular injection plus oral or nasal feeding antiepileptic drugs were used to control the seizure therapy as soon as possible. Results Five patients were controlled within one hour of attack, five patients were controlled within 1-2 hours and three patients were controlled within 6-24 hours. None of the neurological deficits left. Conclusion Diazepam combined with phenobarbital sodium is the first choice of medication to control the status of epilepsy. Valproate has a positive effect on patients with status epilepticus who need to be aware of it. For patients with ineffective conventional therapy, midazolam and propofol Can effectively control the attack.