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目的了解金黄色葡萄球菌医院感染状况及其耐药性,为临床合理选用抗菌药物提供参考依据。方法通过临床调查和病人标本病原学检验方法,对某部队医院住院患者金黄色葡萄球菌感染情况进行调查。结果在调查期间,从该医院住院病人标本中检出金黄色葡萄球菌210株,其中耐甲氧西林金黄色葡萄球菌(MRSA)131株,占62.4%。有62.4%的金黄色葡萄球菌分离自病人痰液标本,表明以呼吸道感染为主。金黄色葡萄球菌感染患者主要分布于重症监护病房(ICU)、呼吸科和神内科。所有检出的金黄色葡萄球菌均对万古霉素和利奈唑胺敏感,只对青霉素和红霉素的耐药率较高。结论该医院金黄色葡萄球菌感染者主要分布于重症病房,MRSA检出率较高,耐药日益严重。
Objective To understand the status of Nosocomial Infection in Staphylococcus aureus and its drug resistance and to provide a reference for the rational use of antibacterials in clinic. Methods The clinical inpatient and patient specimens etiological test methods were used to investigate the prevalence of Staphylococcus aureus inpatients in a military hospital. Results During the investigation, 210 Staphylococcus aureus isolates were detected from the hospital inpatients, of which 131 strains were methicillin-resistant Staphylococcus aureus (MRSA), accounting for 62.4%. 62.4% of Staphylococcus aureus isolated from patients with sputum samples, indicating that the main respiratory tract infection. Patients infected with Staphylococcus aureus are mainly found in intensive care units (ICU), respiratory and neurology. All the S. aureus were detected were sensitive to vancomycin and linezolid, only higher rates of resistance to penicillin and erythromycin. Conclusion The hospital infected with Staphylococcus aureus is mainly distributed in the intensive care unit. The detection rate of MRSA is higher and the drug resistance is more and more serious.