目前盐酸异丙嗪糖浆含量的测定，常采用乙醚多次提取后用酸碱滴定法，且有空白校正。我们通过一阶导数光谱测定其含量，有效地排除辅料的干扰，结果满意。现报告如下。 材料与方法：①实验条件选择：取盐酸异丙嗪适量，用 ０．０１ｍｏｌ／Ｌ盐酸液稀释成 ４０ｕｇ／ｍｌ，以０ At present, the determination of promethazine hydrochloride syrup, often using ether after repeated extraction with acid-base titration, and a blank correction. We determined the content by first-order derivative spectroscopy, effectively eliminating the interference of excipients, with satisfactory results. The report is as follows. MATERIALS AND METHODS: ①Experimental conditions: The appropriate amount of promethazine hydrochloride was diluted to 40ug / ml with 0.01mol / L hydrochloric acid solution and 0