我们以往的工作发现,隔区注射精氨酸加压素(AVP),引起降温作用的机理是由于注射到隔区内的AVP能通过兴奋视前区-下丘脑前部(PO-AH)的热敏感神经元和抑制冷敏感神经元的活动,而致体温降低。应用免疫组化及神经追踪技术的观察结果表明,杏仁内侧也含有大量的AVP神经元。Fedrico等给大鼠杏仁内侧核注射AVP可引起明显的降温效应。我们给家兔杏仁内侧核注射AVP也能使发热效应明显降低。杏仁内侧核注射AVP的抗热作用是否与隔区注射AVP引起的抗热作用一样,也是由于影响了PA-OH温度敏感神经元的活动所致。因此,我们 Our previous work found that the mechanism by which AVP is injected into the compartments to cause cooling is due to the fact that AVP injected into the septum can be activated by stimulating the preoptic area - the front of the hypothalamus (PO-AH) Heat-sensitive neurons and inhibit cold-sensitive neuronal activity, resulting in decreased body temperature. Observations using immunohistochemistry and neuro-tracing techniques show that the medial almond also contains a large number of AVP neurons. Fedrico and other rats to the medial allantoic nucleus injection of AVP can cause significant cooling effect. We injected AVP to the medial alveolar nucleus of rabbits to reduce the fever effect. Whether the antipyretic effect of AVP injected into the medial amygdaloid is the same as that induced by AVP injection into the septum is also due to the effect on the activity of PA-OH temperature-sensitive neurons. therefore, we