炎性肠病是一种自身免疫性疾病,其病因和发病机制至今尚未被完全阐明。多种细胞因子的变化共同参与及免疫紊乱在炎性肠炎发生、发展中起着重要作用。白细胞介素23就是其中的一种,它属于前炎性因子,参与机体控制感染和自身免疫性疾病发生,白细胞介素23诱导CD4+T细胞分化为Th17细胞,在炎性肠病的发病机制中可能处于重要地位。 Inflammatory bowel disease is an autoimmune disease whose etiology and pathogenesis have not yet been fully elucidated. A variety of cytokine changes in the joint participation and immune disorders in the occurrence and development of inflammatory enteritis plays an important role. Interleukin-23 is one of them, which belongs to proinflammatory cytokines and is involved in the control of infection and autoimmune diseases in the body. Interleukin-23 induces the differentiation of CD4 + T cells into Th17 cells. In the pathogenesis of inflammatory bowel disease In may be in an important position.