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注射用美罗培南为碳青霉烯类抗生素,临床上主要用于治疗由敏感菌引起的各种感染,近年来国内有文献报道其配伍禁忌,现概述如下:1与环丙沙星孙小莉等报道,1例换瓣术后成人患者在静脉滴注环丙沙星氯化钠注射液结束后输注美罗培南时出现白色沉淀且堵塞输液器,导致液体无法输注;另1例系换瓣术后患者静滴环丙沙星后续接美罗培南时,出现白色浑浊和沉淀,因及时发现未出现不良反应[1]。经实验证明两药存在配伍禁忌。
Meropenem for injection carbapenem antibiotics, clinically mainly used for the treatment of various infections caused by susceptible strains in recent years, the domestic literature reported its incompatibility, are summarized as follows: 1 and ciprofloxacin Sun Xiaoli and other reports , 1 case of valve replacement adult patients after intravenous infusion of ciprofloxacin sodium injection Meropenem appeared white precipitate and plug the infusion set, resulting in fluid can not be infused; another case of flap valve After the patient intravenous infusion of ciprofloxacin followed by Meropenem, white turbidity and precipitation, as found in time without adverse reactions [1]. The experiment proved that the existence of incompatibility between the two drugs.