大多数的放疗和化疗通过诱导肿瘤细胞凋亡而实现治疗目的。大蒜的脂溶性和水溶性烯丙基硫化物能抑制肿瘤的发生 ,诱导多种肿瘤细胞系凋亡 ,其诱导肿瘤细胞凋亡的作用机制主要包括影响MAPK家族的信号转导通路 ,使细胞内钙稳态失衡 ,促进活性氧的产生 ,活化caspase 3以及影响 p5 3,Bcl 2 ,Bax的表达。 Most radiotherapy and chemotherapy achieve therapeutic goals by inducing tumor cell apoptosis. The fat-soluble and water-soluble allyl sulfide of garlic can inhibit tumorigenesis and induce apoptosis of many tumor cell lines. The mechanism of apoptosis induced by garlicin mainly includes the signal transduction pathway of MAPK family, Calcium steady-state imbalance, promote the production of reactive oxygen species, activation of caspase 3 and affect p5 3, Bcl 2, Bax expression.