论文部分内容阅读
目的分析探讨垂体瘤患者在神经内镜辅助下采用鼻蝶垂体瘤切除治疗的临床疗效。方法选择2013年5月—2014年5月收治的垂体瘤患者50例作为研究对象,随机分为对照组和试验组各25例。对照组在传统显微镜下行垂体瘤切除术,试验组在神经内镜辅助下行鼻蝶垂体瘤切除术。观察两组蛛网膜下腔出血、脑脊液侧漏和外鼻孔缩窄发生情况及神经内镜下使用鼻蝶垂体瘤切除术的临床效果。计量资料采用t检验,计数资料采用χ2检验,P<0.05为差异有统计学意义。结果试验组患者手术时间和创伤面积分别为(30.44±10.02)min、(1.18±0.41)cm2,均明显低于对照组的(61.22±18.23)min、(2.34±0.54)cm2,差异均有统计学意义(t=7.398、8.554,P<0.05)。试验组蛛网膜下腔出血、脑脊液侧漏及鼻孔缩窄发生率分别为4%、0%、4%,均明显低于对照组的32%、28%、32%,差异均有统计学意义(均P<0.05)。试验组总有效率(88%)明显高于对照组(52%),差异有统计学意义(P<0.05)。结论垂体瘤患者经神经内镜下采用鼻蝶垂体瘤切除术治疗,手术时间得以缩短,创伤较小,手术过程简便,安全可靠,应广泛运用在临床。
Objective To analyze the clinical efficacy of pituitary adenoma resection with pituitary adenoma assisted by neuroendoscope. Methods Fifty patients with pituitary adenomas who were treated from May 2013 to May 2014 were selected as study subjects and randomly divided into control group and experimental group of 25 cases. The control group underwent conventional pituitary tumor resection, the experimental group in neurosurgery assisted nasal pituitary resection. The clinical effects of subarachnoid hemorrhage, cerebrospinal fluid lateral leakage and external nostril stenosis and endoscopic pituitary adenoma resection under endoscopy were observed. Measurement data using t test, count data using χ2 test, P <0.05 for the difference was statistically significant. Results The operation time and wound area in the test group were (30.44 ± 10.02) min and (1.18 ± 0.41) cm 2, respectively, which were significantly lower than those in the control group (61.22 ± 18.23) min and (2.34 ± 0.54) cm 2 Significance (t = 7.398, 8.554, P <0.05). The incidences of subarachnoid hemorrhage, cerebrospinal fluid leakage and nasal constriction in the experimental group were 4%, 0% and 4%, respectively, which were significantly lower than those in the control group (32%, 28% and 32%, respectively) (All P <0.05). The total effective rate (88%) in the experimental group was significantly higher than that in the control group (52%), the difference was statistically significant (P <0.05). Conclusions The treatment of pituitary adenoma by endoscopic retrosplenus pituitary adenoma is shortened, the operation time is shortened, the trauma is small, the procedure is simple, safe and reliable, and should be widely used in clinic.