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目的探讨多原发性大肠癌的临床特点、诊断和治疗方法。方法回顾性分析我院1989年~2001年收治的多原发性大肠癌27例的临床资料。结果本组27例均行手术治疗。其中,同时性多原发癌11例中行根治性切除9例,异时性多原发癌15例中再次治疗时行根治术12例。同时性多原发癌的5年生存率与同期大肠单癌相比无明显差别;异时性多原发癌的远期疗效明显好于同期大肠单癌。结论术前全程肠镜检查、术中全大肠探查可提高多原发性大肠癌的诊断率。根治性切除是治疗多原发性大肠癌的治疗原则。
Objective To investigate the clinical features, diagnosis and treatment of multiple primary colorectal cancer. Methods The clinical data of 27 patients with multiple primary colorectal cancer admitted from 1989 to 2001 in our hospital were retrospectively analyzed. Results The group of 27 patients underwent surgical treatment. Among them, there were 9 cases of radical primary resection of multiple primary cancers at the same time and radical resection in 12 cases of 15 cases of metachronous multiple primary cancers. At the same time, there was no significant difference in the 5-year survival rate of multiple primary cancers compared with single colon cancer of the same period. The long-term curative effect of multiple primary cancers was significantly better than single colon cancer of the same period. Conclusion The preoperative total colonoscopy, intraoperative exploration of the whole colon can improve the diagnosis of multiple primary colorectal cancer. Radical resection is the treatment of multiple primary colorectal cancer treatment principles.