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目的探讨C反应蛋白(CRP)、血糖(GLU)、三酰甘油(TG)及淀粉酶(AMS)对急性胰腺炎的临床诊断价值。方法选取120例急性胰腺炎(AP)患者为研究对象,其中重症急性胰腺炎组(SAP)52例,轻症急性胰腺炎组(MAP)68例。选择同期的180名健康人作为对照组,对比各组患者发病后第1、3、5天时外周血内CRP、GLU、TG、AMS水平、症状持续时间。结果发病后第1、3、5天时,CRP、GLU、TG、AMS水平从高到低依次为SAP组、MAP组、健康对照组。SAP组患者症状持续时间均高于MAP组,且差异有统计学意义(P<0.05)。血清CRP、GLU、TG、AMS水平与腹痛、高热、呕吐的持续时间均呈正相关。结论血清CRP、GLU、TG水平与AP的症状持续时间及病情密切相关,可作为SAP诊治的重要临床依据。
Objective To investigate the clinical value of C-reactive protein (CRP), blood glucose (GLU), triglyceride (TG) and amylase (AMS) in the diagnosis of acute pancreatitis. Methods A total of 120 patients with acute pancreatitis (AP) were selected as study objects, including 52 cases of severe acute pancreatitis (SAP) and 68 cases of mild acute pancreatitis (MAP). A total of 180 healthy people were selected as the control group to compare the levels of CRP, GLU, TG and AMS in the peripheral blood and the duration of symptoms on the 1st, 3rd, 5th day after the onset of illness in each group. Results The levels of CRP, GLU, TG and AMS decreased from high to low on the 1st, 3rd and 5th day after onset to SAP group, MAP group and healthy control group. The duration of symptoms in SAP group was higher than that in MAP group, and the difference was statistically significant (P <0.05). Serum CRP, GLU, TG, AMS levels and abdominal pain, fever, vomiting duration were positively correlated. Conclusion Serum CRP, GLU and TG levels are closely related to the duration and severity of AP symptoms and can be used as an important clinical basis for the diagnosis and treatment of SAP.