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本文报道了减量米非司酮合并应用三苯氧胺20mg 2次/日,共两天,第4天加用卡前列甲酯栓1mg 终止早孕(孕天≤49天)的临床多中心随机对比性研究。结果加用与不加用三苯氧胺两组的完全流产率、不全流产第和失败率分别为91.5%、93.4%,4.8%、4.7%和3.7%、1.9%;出血天数分别为17.2±11.2和18.5±11.6天。两组在临床效果、出血情况和副反应等方面基本相似。表明加用三苯氧胺不能提高完全流产率,也不减少流产后出血天数和出血量
This article reports the reduction of mifepristone combined with tamoxifen 20mg 2 times / day, a total of two days, the first 4 days plus cardinal methylester suppository 1mg termination of early pregnancy (pregnant day ≤ 49 days) clinical multicenter randomized controlled study . Results The rates of complete abortion and incomplete abortion were 91.5%, 93.4%, 4.8%, 4.7% and 3.7%, 1.9% respectively with and without tamoxifen. The bleeding days were 17.2 ± 11.2 and 18.5 ± 11.6 days. The two groups in the clinical effects, bleeding and side effects were similar. Show that with tamoxifen can not increase the rate of complete abortion, nor reduce the number of bleeding days after abortion and bleeding