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目的探讨O型血孕妇孕期血清IgG抗体效价与新生儿ABO溶血病发生的关系。方法对夫妻ABO血型不合的O型血孕妇,孕期进行IgG抗A(B)抗体效价测定,分娩的新生儿脐血做免疫血清学检验。结果孕妇IgG抗体效价依次增高,新生儿溶血病发生率也逐渐增高(P<0.05)。结论产前测定孕妇血清IgG抗A(B)抗体,对围产期保健有一定意义。
Objective To investigate the relationship between serum IgG antibody titers in pregnant women with O-type blood during pregnancy and ABO hemolytic disease in neonates. Methods The pregnant women with O-type blood incompatible with ABO were tested for anti-A (B) antibody titer during pregnancy. The neonatal umbilical blood for childbirth was tested for immune serology. Results IgG antibody titer of pregnant women in turn increased, the incidence of hemolytic disease also increased gradually (P <0.05). Conclusion Prenatal determination of serum IgG anti-A (B) antibodies in pregnant women has some significance for perinatal health care.