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肿瘤的无创诊断是指采用非侵入性检测方法,而不是纤维内镜、病理活检、X线检查等主流诊疗技术来诊断肿瘤的手段,而是对血、尿、粪便、唾液、痰等生物样本内进行DNA甲基化分析、微生物感染状况分析、脱落肿瘤细胞或游离DNA分析、肿瘤抗原分析、小分子代谢物分析等。近日,笔者所在的课题组成功地从胃癌患者的尿样中筛选到一组具有鉴别胃癌与非癌人群的小分子代谢物,并提出这些尿液小分子代谢物具备作为胃癌诊断标志物的
Tumor noninvasive diagnosis refers to the use of non-invasive detection methods, rather than fiber endoscopy, biopsy, X-ray examination and other mainstream diagnostic techniques to diagnose cancer means, but blood, urine, stool, saliva, sputum and other biological samples DNA methylation analysis, microbial infection status analysis, shedding of tumor cells or free DNA analysis, tumor antigen analysis, analysis of small molecule metabolites. Recently, the author’s research group successfully screened a group of small molecule metabolites that differentiate between gastric cancer and non-cancer patients from the urine samples of gastric cancer patients and proposed that these small-molecule metabolites of urine have the diagnostic marker of gastric cancer