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目的 了解肝硬化患者血清心肌肌钙蛋白Ⅰ水平的变化及其与肝功能损害以及与门脉高压的相关性。方法 采用微粒子化学发光全自动免疫分析系统测定 40例肝硬化患者血清肌钙蛋白Ⅰ水平 ,用彩色超声仪测定门脉主干内径。结果 肝硬化患者血清肌钙蛋白Ⅰ水平显著增高 ,血清肌钙蛋白Ⅰ水平与肝功能及门脉高压无明显相关。结论 心肌肌钙蛋白Ⅰ是了解肝硬化患者有否心肌损伤的敏感指标。
Objective To investigate the changes of serum cardiac troponin Ⅰ level in cirrhotic patients and its relationship with liver dysfunction and portal hypertension. Methods Serum troponin I levels were measured in 40 patients with cirrhosis by using particle chemiluminescence immunoassay system. The diameter of the main portal vein was measured by color sonography. Results The serum level of troponin Ⅰ in patients with cirrhosis was significantly increased. Serum troponin Ⅰ level was not significantly correlated with liver function and portal hypertension. Conclusions Cardiac troponin I is a sensitive indicator of myocardial damage in patients with cirrhosis.