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目的探讨手足口病重症病例的流行特征。方法采用Epidata数据库进行数据的录入,利用Excel2003软件,通过卡方检验对率的比较进行统计学分析。结果 322例手足口病重症病例年龄分布3岁以下儿童占90.38%,5～6月份发生率71.12%,临床表现上有易惊、手足抖动分别为82.92%、57.45%,EV71病毒实验室检出率为76.71%,明显高于一般病例EV71检出率。结论 HFMD重症病例以农村地区3岁以下散居儿童发病为主,发生时间与一般病例分布一致,临床表现上常有手足抖动、易惊等神经系统受累表现,多由EV71病毒基因型引起。
Objective To explore the prevalence of severe cases of hand-foot-mouth disease. Methods Epidata database was used for data entry. Excel2003 software was used to compare the rates by chi-square test. Results The age distribution of 322 cases of hand, foot and mouth disease in severe cases accounted for 90.38% of children under 3 years old. The incidence was 71.12% in May to June. The clinical manifestations were easily scared, hand-foot jitter was 82.92% and 57.45%, respectively. EV71 virus laboratory Rate of 76.71%, significantly higher than the detection rate of EV71 cases. Conclusions Severe HFMD cases are mainly occurred in children under 3 years of age in rural areas. The incidence of HFMD is consistent with the distribution of common cases. The clinical manifestations are often nervous system involvement such as hand-foot jitter and easy-to-shock, which are mostly caused by EV71 virus genotype.