鼻咽血管纤维瘤好发于青年男性,占头颈部肿瘤的0.5%。多起源于蝶腭孔附近,富血管,易出血,常影响患者的生活质量,重者可引起严重的颅内外并发症,甚至危及生命。鼻咽血管纤维瘤的形成及发病机制有多种学说,但其确切机制尚未完全阐明。本文就鼻咽血管纤维瘤分子机制研究进展做一综述。 Nasopharyngeal angiofibroma occurs in young men, accounting for 0.5% of head and neck cancer. Many originated in the sphenopalatine foramen near the rich blood vessels, bleeding, often affect the quality of life of patients, severe cases can cause serious intracranial complications, and even life-threatening. There are many theories about the formation and pathogenesis of nasopharyngeal angiofibroma, but its exact mechanism has not been fully elucidated. This article reviews the molecular mechanism of nasopharyngeal angiofibroma.