先证者(Ⅲ8)男性,36岁。出生时发现多指(趾),手12指,足12趾。2岁左右出现双眼视力不好,随年龄的增加视力下降。智力障碍,青少年期开始出现向心性肥胖。婚后无子女。睾丸小,阴茎短小。Ⅲ9,女,34岁。出生时发现多指(趾),手11指,足12趾。2岁左右出现双眼视力不好,随年龄的增加视力 Probate (III8) male, 36 years old. Fingered more fingers (toes) at birth, hand 12 fingers, feet 12 toes. 2-year-old binocular vision is not good, with increased visual acuity decreased. Mental retardation, adolescent onset of central obesity. No children after marriage. Testicular small, short penis. Ⅲ9, female, 34 years old. Fingered more fingers (toes), hand 11 fingers, feet 12 toes. 2-year-old binocular vision is not good, with increased visual acuity