甲状腺癌是最常见的内分泌系统恶性肿瘤,发病率在世界范围内呈逐年上升趋势。尽管大多数甲状腺癌临床过程相对缓慢,手术、药物抑制和放射性核素治疗效果良好;但仍有部分甲状腺癌表现为侵袭性生物学行为,局部外侵严重,预后较差,包括局部进展或复发的分化型甲状腺癌、髓样癌及所有的未分化癌。在甲状腺乳头状癌的变型中,高细胞型弥漫硬化型柱状细胞型实体型梁状型和局 Thyroid cancer is the most common endocrine system malignancy, the incidence in the world showed a rising trend year by year. Although most thyroid cancers are relatively slow in clinical practice, surgery, drug suppression and radionuclide therapy are effective; however, some thyroid carcinomas still show aggressive biological behavior with severe local invasion and poor prognosis, including local progression or recurrence Of differentiated thyroid cancer, medullary carcinoma and all undifferentiated carcinoma. In a variant of papillary thyroid carcinoma, the high cell type diffusely hardened columnar cell type solid beam type and the