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目的探讨急性冠脉综合征患者合并糖代谢异常情况,及其对ACS患者近期预后的影响。方法 145例急性冠脉综合症患者根据病史及住院5-7d的口服葡萄糖耐量试验(OGTT)结果将患者分为正常糖耐量组、糖耐量减低组、空腹血糖受损组、糖尿病组四组,分别观察各组近期(30d)病死率及心力衰竭、心源性休克、心律失常、肺部感染等并发症发生情况。结果糖耐量减低组、空腹血糖受损组、糖尿病组与正常糖耐量组比较,其严重心律失常、心力衰竭、肺部感染、心源性休克的发生率高。糖尿病组及糖耐量减低组与空腹血糖受损组比较,差异也有统计学意义。结论各种糖代谢异常不同程度地增加急性冠脉综合症患者并发症的发生率,增加病死率。
Objective To investigate the abnormal glucose metabolism in patients with acute coronary syndrome and its effect on the short-term prognosis of patients with ACS. Methods 145 patients with acute coronary syndrome (ACS) were divided into four groups: normal glucose tolerance group, impaired glucose tolerance group, impaired fasting glucose group and diabetes mellitus group according to their medical history and oral glucose tolerance test (OGTT) The morbidity and complications such as heart failure, cardiogenic shock, arrhythmia and pulmonary infection in each group were observed respectively. Results Compared with normal glucose tolerance group, patients with impaired glucose tolerance, impaired fasting glucose, diabetes mellitus had higher incidence of severe arrhythmia, heart failure, pulmonary infection and cardiogenic shock. There was also a significant difference between diabetic group and impaired glucose tolerance group and impaired fasting glucose group. Conclusion All kinds of abnormal glucose metabolism increased the incidence of complications and increased the mortality in patients with acute coronary syndromes to varying degrees.