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目的观察人血静脉丙种球蛋白(IVIG)治疗小儿毛细支气管炎的临床疗效。方法将2010年5月-2012年5月我院收治的100例毛细支气管炎患儿随机分为对照组和治疗组各50例,对照组50例给予常规综合治疗,治疗组在对照组基础上加用IVIG,比较两组患儿的临床疗效、咳喘、喘憋、肺部体征消失时间、住院时间。结果治疗组咳嗽、喘憋、肺部湿啰音消失时间均较对照组快,住院时间也较对照组短,P<0.05;治疗组总有效率96.0%,对照组总有效率82.0%,治疗组总有效率显著高于对照组,P<0.05;治疗组随访中哮喘发生率为20.0%,对照组48.84%,治疗组哮喘发生率显著低于对照组,P<0.05。结论 IVIG治疗小儿毛细支气管炎临床疗效好,而且操作方便,无不良反应,是治疗小儿毛细支气管炎快速而有效的药物,值得临床推广应用。
Objective To observe the clinical efficacy of intravenous gamma globulin (IVIG) in the treatment of children with bronchiolitis. Methods From May 2010 to May 2012, 100 children with bronchiolitis admitted to our hospital were randomly divided into control group and treatment group, 50 cases in each group. 50 cases in control group were given conventional comprehensive treatment. On the basis of the control group Add IVIG, the clinical efficacy of two groups were compared, cough, wheezing, disappearance of lung signs, hospital stay. Results The treatment group cough, wheezing, pulmonary wet rales disappeared faster than the control group, hospitalization time shorter than the control group, P <0.05; the total effective rate was 96.0% in the control group, the control group, the total effective rate was 82.0%, treatment The total effective rate in the treatment group was significantly higher than that in the control group (P <0.05). The incidence of asthma was 20.0% in the treatment group and 48.84% in the control group. The incidence of asthma in the treatment group was significantly lower than that in the control group (P <0.05). Conclusion IVIG treatment of children with bronchiolitis clinical efficacy, and easy to operate, no adverse reactions, is the treatment of children with bronchiolitis rapid and effective drug, worthy of clinical application.