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目的:探讨在甲状腺癌手术中采用纳米碳淋巴示踪剂保护甲状旁腺的作用。方法:245例甲状腺癌患者随机均分为常规组和纳米碳组,比较两组中央区淋巴结脂肪组织中误切的甲状旁腺检获情况及术后血钙、甲状旁腺素(PTH)改变情况。结果:纳米碳组一过性低钙血症症状发生率13.33%明显低于常规组32.90%,差异具有统计学意义(P<0.05);纳米碳组永久性低钙血症发生率0,常规组1.29%,差异无统计学意义(P>0.05);纳米碳组PTH暂时性减低发生率11.11%低于常规组29.68%,差异具有统计学意义(P<0.05)。PTH永久性减低纳米碳组未发生,常规组1.29%,差异无统计学意义(P>0.05)。病理检查证实纳米碳组检获误切甲状旁腺率4.44%明显低于常规组12.90%,差异具有统计学意义(P<0.05)。结论:应用纳米碳负显影在甲状腺癌手术中可起到辨认和保护甲状旁腺的作用。
Objective: To investigate the effect of nanocarbon lymphatic tracer on the parathyroid gland in thyroid cancer surgery. Methods: A total of 245 patients with thyroid cancer were randomly divided into conventional group and carbon nanocarbon group. The false parathyroid seizures and the changes of postoperative serum calcium and parathyroid hormone (PTH) in the central lymph node adipose tissue were compared between the two groups . Results: The incidence of transient hypocalcemia in the carbon nanocarbon group was significantly lower than that in the conventional group (13.33% vs 32.90%, P <0.05), and the incidence of permanent hypocalcemia in the carbon nanocarbon group was 0 Group (1.29%), the difference was not statistically significant (P> 0.05). The incidence of transient decrease of PTH in carbon nanocarbon group was 11.11% lower than that in routine group (29.68%), the difference was statistically significant (P <0.05). PTH permanent reduction of carbon nano group did not occur, the conventional group 1.29%, the difference was not statistically significant (P> 0.05). Pathological examination confirmed that the false-cut parathyroid gland in the carbon nanocapture group was 4.44%, which was significantly lower than that in the conventional group (12.90%, P <0.05). Conclusion: The application of nano-carbon negative imaging in thyroid cancer surgery can play a role in identifying and protecting the parathyroid.