目的探讨肝病患者红细胞免疫功能的动态变化。方法　采用郭峰法检测红细胞C3b受体花环率 (RCR)、循环免疫复合物花环率 (RICR)、红细胞免疫促进因子 (RFER)和红细胞免疫抑制因子 (RFIR) ,并与正常对照相比较。结果肝病患者RCR及RFER明显低于对照组 (P <0 0 1) ,RICR及RFIR明显高于对照组 (P <0 0 1) ;RCR与RFER成正相关 (P <0 0 1) ,与RFIR成负相关 (P <0 0 1)。结论肝病患者红细胞免疫功能下降 ,自我调控紊乱。肝病的发生发展与机体红细胞免疫功能有关。 Objective To investigate the dynamic changes of erythrocyte immune function in patients with liver disease. Methods The RBC, RICR, RFER and RFIR of erythrocyte C3b receptor were detected by GuoFeng method and compared with the normal control. Results RCR and RFER in patients with liver disease were significantly lower than those in control group (P <0.01), RICR and RFIR were significantly higher than those in control group (P <0.01); RCR was positively correlated with RFER (P <0.01) A negative correlation (P <0.01). Conclusion Hepatic disease patients with decreased immune function, self-regulation disorder. The occurrence and development of liver disease and the body’s red blood cell immune function.