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目的总结原发性胆囊癌的外科诊治体会。方法回顾性分析本院治疗的56例原发性胆囊癌的诊治资料。结果本组患者行单纯胆囊切除、标准根治术等外科治疗。病理学检查结果示腺癌37例(66.1%),黏液腺癌8例(14.3%),鳞状细胞癌7例(12.5%),类癌4例(7.2%)。按Nevin分期,I期5例(8.9%),Ⅱ期7例(12.5%),Ⅲ期12例(21.4%),Ⅳ期20例(35.7%),V期12例(12.5%)。随访49例(87.5%),存活1年以上18例,1年内死于肿瘤31例,1年生存率为36.7%。术后并发症发生率为5.4%。结论外科手术是治疗原发性胆囊癌的首选方法,早期诊断和早期根治性手术对提高原发性胆囊癌患者的生存率具有重要意义。
Objective To summarize the experience of surgical diagnosis and treatment of primary gallbladder cancer. Methods The clinical data of 56 cases of primary gallbladder carcinoma treated in our hospital were analyzed retrospectively. Results This group of patients underwent simple cholecystectomy, standard radical mastectomy and other surgical treatment. The results of pathological examination showed that adenocarcinoma was found in 37 cases (66.1%), mucinous adenocarcinoma in 8 cases (14.3%), squamous cell carcinoma in 7 cases (12.5%) and carcinoid carcinoid in 4 cases (7.2%). According to the Nevin staging, there were 5 cases (8.9%) in stage I, 7 cases (12.5%) in stage II, 12 cases (21.4%) in stage III, 20 cases (35.7%) in stage IV and 12 cases (12.5%) in stage V. Follow-up in 49 cases (87.5%), survived for more than 1 year in 18 cases, died of tumor in 1 year 31 cases, 1-year survival rate was 36.7%. The incidence of postoperative complications was 5.4%. Conclusion Surgery is the first choice for the treatment of primary gallbladder cancer. Early diagnosis and early radical operation are important for improving the survival rate of patients with primary gallbladder cancer.