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目的探讨某高校教职工脂肪肝发生的危险因素及其与代谢综合征的关系,为高校教职工脂肪肝的预防提供依据。方法采用横断面研究方法,以沈阳市某大学1 063名在职及退休教职工为研究对象,进行人体测量、血液检测及腹部B超检查。结果教职工脂肪肝检出率为34.6%,男性(40.5%)显著高于女性(27.6%)(P<0.01)。调整年龄、性别后,超重、肥胖、中心型肥胖、高三酰甘油、高胆固醇、高血糖者患脂肪肝的危险度分别是正常者的14.32,3.45,2.65,3.14,1.71,1.71倍(P值均<0.05),且高三酰甘油、高胆固醇、高血糖的作用独立于肥胖。调整年龄、性别、体质量指数后,脂肪肝者患代谢综合征的危险度是正常者的3.44倍(P<0.05)。结论肥胖、高三酰甘油、高胆固醇、高血糖是脂肪肝的独立危险因素,罹患脂肪肝患代谢综合征的危险度较高。
Objective To explore the risk factors of fatty liver and its relationship with metabolic syndrome in a university faculty and to provide basis for the prevention of fatty liver in faculty. Methods A cross-sectional study was conducted with 1 063 serving and retired staff members in a university in Shenyang City for anthropometric, blood tests and abdominal B-ultrasound. Results The detection rate of fatty liver in teaching staff was 34.6%, while that in male (40.5%) was significantly higher than that in female (27.6%) (P <0.01). The risk of fatty liver in overweight, obesity, central obesity, hypertriglyceridemia, hypercholesterolemia and hyperglycemia were 14.32,3.45,2.65,3.14,1.71,1.71 times (P value All <0.05), and high triglyceride, high cholesterol, high blood sugar independent of obesity. After adjusting for age, sex and body mass index, the risk of metabolic syndrome in fatty liver was 3.44 times of normal (P <0.05). Conclusion Obesity, hypertriglyceride, hypercholesterolemia and hyperglycemia are independent risk factors for fatty liver and have a higher risk of having metabolic syndrome with fatty liver.