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目的:探讨克林霉素联合庆大霉素治疗慢性盆腔炎的临床效果。方法:将120例慢性盆腔炎患者随机分对照组与观察组各60例,对照组患者给予庆大霉素24万单位加入500 ml生理盐水静点,每日1次;甲硝唑0.5g,每日2次静点。观察组患者给予克林霉素磷酸酯600 mg加入生理盐水500 ml静点,每日两次;庆大霉素24万单位加入500ml生理盐水静点,每日1次。两组疗程均为1周,连续治疗2个疗程,比较两组临床治疗效果及症状积分。结果:观察组与对照组治疗总有效率分别为96.7%和83.3%,差异有统计学意义(P<0.01);治疗前两组症状积分无明显差异,治疗后观察组症状积分显著低于对照组,差异有统计学意义(P<0.01)。结论:克林霉素联合庆大霉素治疗慢性盆腔炎疗效确切,不良反应少,值得在临床推广。
Objective: To investigate the clinical effect of clindamycin combined with gentamicin in the treatment of chronic pelvic inflammatory disease. Methods: A total of 120 patients with chronic pelvic inflammatory disease were randomly divided into control group and observation group, 60 cases in each group. Gentamicin 240,000 units were added to 500 ml physiological saline once a day in the control group. Metronidazole 0.5 g, Twice daily static point. Patients in the observation group were given clindamycin phosphate 600 mg twice a day at normal saline 500 ml; gentamicin 240 000 units were added to 500 ml normal saline once daily. Two courses of treatment were 1 week, continuous treatment of 2 courses, the clinical efficacy of the two groups and symptom scores. Results: The total effective rates of the observation group and the control group were 96.7% and 83.3%, respectively, with statistical significance (P <0.01). There was no significant difference in the symptom scores between the two groups before treatment, and after treatment, the symptom scores of the observation group were significantly lower than those of the control group Group, the difference was statistically significant (P <0.01). Conclusion: Clindamycin combined with gentamicin for the treatment of chronic pelvic inflammatory disease is effective and has few adverse reactions. It is worthy of clinical promotion.