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RDB是将我们设计的HPV6B、11、16、18、31、33、35的7个序列特异性寡核苷酸（SSO）探针分别依次固定在尼龙膜上，再与经PCR扩增的DNA靶序列杂交，即可在同一张膜上分辨7型HPVDNA的任一型。我们检测尖锐湿疣患者62例，对其中20例进行组织活检，阳性检出率为950（19／20）。阳性检出中，HPV6B型8例（40．0％）、HPV11型9例（45．0％）、HPV6B／11型（混合型）2例（10．0％）；对其中42例进行宫颈抹片检测，阳性检出率为92．9％（39／42）。阳性检出中，HPV6B型15例（35．7％）、HPV11型19例（45．2％）、HPV6B／11型3例（7.1％）、HPV16型2例（4．8％）。结果表明尖锐湿疣患者检出HPV总阳性率为94％，感染HPV型主要为HPV6B及11型。
RDB is designed by our design of HPV6B, 11,16,18,31,33,35 seven sequence-specific oligonucleotide (SSO) probe were sequentially fixed on the nylon membrane, and then with the PCR amplified DNA The target sequence hybridizes to distinguish any type 7 HPVDNA on the same membrane. We detected 62 cases of condylomata, biopsy of which 20 cases, the positive detection rate was 950 (19/20). Among the positive samples, 8 (40.0%) were HPV6B, 9 (45.0%) were HPV11 and 2 (10.0%) were HPV6B / 11 Pap test, the positive detection rate was 92.9% (39/42). Among the positive cases, 15 (35.7%) were HPV6B, 19 (45.2%) were HPV11, 3 (7.1%) were HPV6B / 11 and 2 were HPV16 (4.8%). The results showed that the total positive rate of HPV detection in patients with condyloma acuminatum was 94%, HPV type HPV6B and type 11 were mainly infected.