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目的 研究煤烟污染与女性肺癌的关系。方法 对115例女性原发性肺癌患者进行单因素Logistic分析。采用昆明种小鼠240只，随机分为对照组和煤烟组，使煤烟组自然吸入不同剂量煤烟。结果 女性肺癌危险性随煤烟污染指数的增大而增高(χ2=15.31, P<0.005)。小鼠煤烟组总的肺癌发生率显著高于对照组(χ2 =5.88, P <0.01)，且煤烟量和发病率呈剂量─效应关系。结论 煤烟污染可能是女性肺癌的重要病因因素。
Objective To study the relationship between soot pollution and female lung cancer. Methods Single factor Logistic analysis was performed on 115 female patients with primary lung cancer. 240 Kunming mice were randomly divided into control group and soot group, so that the soot group naturally inhaled different doses of soot. Results The risk of female lung cancer increased with the increase of coal pollution index (χ2=15.31, P<0.005). The incidence of lung cancer in the mouse soot group was significantly higher than that in the control group (χ2 = 5.88, P <0.01), and the dose-effect relationship between soot volume and incidence was observed. Conclusion Soot pollution may be an important cause of female lung cancer.