目的　探讨周围静脉营养在早产儿治疗中的应用价值及安全性。方法　将94例早产儿随机分为观察组(45例)和对照组(49例),观察组经周围静脉用微电脑输液泵在16~24 h内均匀输入静脉营养液,对照组给予一般综合治疗。结果　观察组患儿生后4~8 d体重开始增加,每天增重10~33 g,平均(24 22±8 61)g,对照组于生后8~14 d开始增加体重,每天增重8~19 g,平均(14 53±4 26)g,两组比较差异有显著意义(P<0 01)。观察组发生并发症8例(17.77%),对照组23例(46.93%),两组比较差异有显著意义(P<0.01)。观察组患儿死亡2例(4.44%),对照组7例(14.28%),两组比较差异有显著意义(P<0.05)。结论　周围静脉营养能使早产儿更早更快的增加体重,减少并发症,降低死亡率,提高早产儿的存活率和生存质量。 Objective To investigate the value and safety of peripheral venous nutrition in the treatment of premature infants. Methods Ninety-four preterm infants were randomly divided into observation group (n = 45) and control group (n = 49). In the observation group, intravenous nutrient solution was infused evenly through the peripheral vein with microcomputer infusion pump within 16-24 h, while the control group received general composite therapy . Results The body weight of the observation group began to increase 4 ~ 8 d after birth, the daily gain was 10 ~ 33 g, with an average of (24 22 ± 8 61) g. The control group started to gain weight 8 ~ 14 d after birth, ~ 19 g, an average of (14 53 ± 4 26) g, the difference between the two groups was significant (P <0.01). There were 8 cases (17.77%) in the observation group and 23 cases (46.93%) in the control group. There was significant difference between the two groups (P <0.01). There were 2 deaths (4.44%) in the observation group and 7 cases (14.28%) in the control group, with significant difference between the two groups (P <0.05). Conclusion Peripheral nourishment can make premature infants earlier and faster increase body weight, reduce complications, reduce mortality and improve the survival rate and quality of life of premature infants.