论文部分内容阅读
目的探讨上皮性卵巢癌患者术前PLT计数增高的临床意义.方法选择临床明确诊断的上皮性卵巢癌患者93例(卵巢癌组)、卵巢良性疾病患者40例(卵巢良性疾病组)及健康体检者40例(健康对照组).取患者术前晨起空腹静脉血检测血小板(PLT)计数及血清CA125水平,结合临床资料进行统计分析.结果卵巢癌组PLT计数为277.6±96.2(*109/L),PLT计数升高47例(41.8%),均明显高于卵巢良性疾病组和健康对照组,差异有统计学意义(P<0.05).晚期上皮性卵巢癌患者PLT计数明显高于早期患者(P<0.005).淋巴结转移的晚期上皮性卵巢癌患者PLT计数显著高于无淋巴结转移者(P<0.005).晚期上皮性卵巢癌患者PLT计数与血清CA125水平具有正相关性,(r=0.540,P<0.01)有统计学意义.结论 PLT计数增高可作为判断术前上皮性卵巢癌患者不良预后的指标之一.“,”Aim To investigate the clinical value of higher platelete in preoperative patients with epithilial ovarian cancer.Methods The study included the ovarian cancer group(n=93),benign ovarian diseases group(n=40) and healthy control group(n=40).The platelete and serum CA125 were measured in the study groups.The data would be analyzed combing with the clinical information.Results The platelete count was higher in ovarian diseases group((277.6±96.2)*109/L) than in benign ovarian diseases group and healthy control group,there was significance statisitical difference(P<0.05).The platelete count was higher in late-ovarian patients than that in pre-ovarian patients.The platelete count was higher in late-ovarian patients with lymphonodus metastasis than that without lymphonodus metastasis patients.The platelete count was correlation to the serum CA125(r=0.54,P<0.01).Conclusion The higher platelete count may be a prognostic marker in the patients with epithilial ovarian cancer.